NANP Board Practice Exam

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Prepare for the NANP Board Exam. Study with detailed questions and explanations on key topics. Enhance your understanding and boost your confidence for the exam.

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What are the products of the Pentose Phosphate Pathway?

ATP and NADH
NADPH and ribose 5-phosphate
NADPH and pyruvate
NADPH and FADH2

The correct answer is: NADPH and ribose 5-phosphate

The Pentose Phosphate Pathway (PPP) primarily produces NADPH and ribose 5-phosphate. NADPH is crucial for reductive biosynthesis and acts as a reducing agent in various anabolic reactions, including fatty acid synthesis and the maintenance of cellular redox balance. Ribose 5-phosphate is essential for the synthesis of nucleotides and nucleic acids, making it vital for DNA and RNA production. While ATP and NADH, as indicated in other choices, are products associated with different metabolic pathways like glycolysis and the citric acid cycle, they are not produced in significant amounts during the PPP. Similarly, pyruvate and FADH2 are also not direct products of this pathway. Pyruvate is generated from glycolysis, while FADH2 is produced during the citric acid cycle. Thus, B correctly identifies the main outputs of the Pentose Phosphate Pathway, highlighting its role in cellular metabolism beyond energy production.