NANP Board Practice Exam

Glycogen turnover refers to which two processes?

1. Glycogenesis and glycolysis

2. Glycogenolysis and gluconeogenesis

3. Glycogenolysis and lipogenesis

4. Glycogen synthesis and glycogenolysis

The correct answer is: Glycogen synthesis and glycogenolysis

Glycogen turnover is a term used to describe the processes that involve the synthesis and degradation of glycogen, which is the stored form of glucose in the body. The correct answer highlights glycogen synthesis, known as glycogenesis, and glycogenolysis, which is the breakdown of glycogen into glucose. In this context, glycogenesis occurs when the body needs to store glucose that is in excess, converting it into glycogen primarily in the liver and muscle tissues. Conversely, glycogenolysis is essential for releasing glucose into the bloodstream during periods of fasting or increased energy demand, providing the necessary fuel for bodily functions and physical activity. The other processes mentioned in the incorrect choices do not encapsulate the dual nature of glycogen turnover effectively. While glycolysis is the breakdown of glucose for energy, it doesn't encompass the storage aspect of glucose. Gluconeogenesis refers to the synthesis of glucose from non-carbohydrate sources, which is distinct from the regulation of glycogen levels in the body. Lipogenesis focuses on converting excess carbohydrates into fats and also does not relate directly to glycogen turnover. Thus, the combination of glycogen synthesis and breakdown in the correct answer aligns perfectly with the definition and understanding of glycogen turnover.